Benjamin D. Heuberger, Ph.D.

Prior to joining K&L Gates, Benjamin was a patent agent in the Boston office of a national law firm.

• American Chemical Society

• “Dovetailing Academia and IP Protection,” Chemistry 252/253 Seminar — University of California, Riverside, May 2017
• “Selecting for a Sequence-General RNA-based RNA-Helix Recognition Motif,” HHMI Janelia Farm - From the RNA World to the Clinic — Ashburn, VA, September 2010

• “Replacing Uridine with 2-Thiouridine Enhances the Rate and Fidelity of Nonenzymatic RNA primer Extension,” Journal of the American Chemical Society, 137, 2769-2775, 2015
• “Crystal Structure Studies of RNA Duplexes Containing s2U:A and s2U:U Base Pairs,” Journal of the American Chemical Society, 136, 13916-13924, 2014
• “Solution Structure of a Parallel-Stranded Oligoisoguanine DNA Pentaplex Formed by d[T(iG)4T] in the Presence of Cs+ Ions,” Angewandte Chemie Int. Ed. 2012, 51, 7952-7955
• “Combinatorial Synthesis of Thrombin-Binding Aptamers Containing iso-Guanine,” Journal of Combinatorial Chemistry, 11, 364-369, 2009
• “A Pre-RNA Candidate Revisited: Both Enantiomers of Flexible Nucleoside Triphosphates are DNA Polymerase Substrates,” Journal of the American Chemical Society, 130, 412-413, 2008
• “Two Watson–Crick-like Metallo Base Pairs,” Organic Letters, 10, 1091-1094, 2008
• “An Alternative Nucleobase Code: Characterization of Purine–Purine DNA Double Helices Bearing Guanine–Isoguanine and Diaminopurine 7-Deaza-Xanthine Base Pairs,” ChemBioChem, 9, 2779-2783, 2008
• “Nonenzymatic Oligomerization of RNA by TNA Templates,” Organic Letters, 8, 5809-5811, 2006
• “A Purine-like Nickel(II) Base Pair for DNA,” Angewandte Chemie Int. Ed. 2005, 44, 1529-1532